At the John T. Vucurevich Cancer Care Institute, we believe that a person diagnosed with cancer shouldn’t have to travel to Colorado or Minnesota to receive state-of-the-art care. Since opening its doors in 1993, the Cancer Care Institute at Rapid City Regional Hospital has provided care for more than 10,000 patients fighting cancer. Conveniently located adjacent to the main Hospital, the Cancer Care Institute provides both inpatient and outpatient medical and radiation oncology services, supportive laboratory and imaging services, and related clinical trial research services.

Regional Hospital’s cancer program has received continuous, full approval as a comprehensive community hospital cancer program from the American College of Surgeon's (ACoS) since 1981. ACoS approval is widely recognized by the Joint Commission of Accredited Healthcare Organizations and other entities, including the American Cancer Society and the Association of Community Cancer Centers, as a "Gold Standard" for cancer programming.

Our vision for providing everyone in our region with the highest quality, progressive quality treatment has been recognized nationally. In 2002,the Cancer Care Institute was awarded a $5.4 million grant from the National Cancer Institute to investigate health disparities and improve cancer treatment for American Indians and was selected as one of only nine institutions nationwide to receive tomotherapy, a revolutionary new radiation delivery system to treat cancer patients.